Disorders of sex development

Disorders of Sex Development

The birth of a new baby is one of the most dramatic events in a family, and the first question is usually "is it a boy or a girl?" The newborn infant with ambiguous external genitalia often comes as a surprise for the doctors as well as the parents and is sometimes described as an endocrine emergency situation presenting a problem of sex assignment. The nomenclature such as 'intersex', 'hermaph...

Disorders of sex development

a Canakkale Onsekiz Mart University, Medical Faculty, Department of Urology, Canakkale, Turkey b Inönü University, Medical Faculty, Department of Urology, Malatya, Turkey c Canakkale Onsekiz Mart University, Medical Faculty, Department of Children Disease, Canakkale, Turkey d Canakkale Onsekiz Mart University, Medical Faculty, Department of Obstetric and Gynecology, Canakkale, Turkey e Canakkal...

Disorders of Sex Development

Introduction Sexual differentiation is the process of development of the differences between male and female from an undifferentiated zygote (fertilised egg). Sex and gender are both important determinants of health. The term “gender” describes those characteristics of females and males that are largely socially created, whereas “sex” encompasses those characteristics that are biologically dete...

Disorders in Human Sex Development

Genetic Screening of Iranian Patients with 46,XY Disorders of Sex Development

Background: Disorders of sex development (DSDs) belong to uncommon pathologies and result from abnormalities during gonadal determination and differentiation. Various gene mutations involved in gonadal determination and differentiation have been associated with gonadal dysgenesis. Despite advances in exploration of genes and mechanisms involved in sex disorders, most children with severe 46,XY ...